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Safety Profile of TRT

28 November 2024 | 

Is Testosterone Replacement Therapy Safe?

Broadly speaking, yes, is safe. indicates that therpay is considered safe in most men, and can also beneficial in improving quality of life.


As a clinic with a strict patient-first approach, we will always make sure that the treatment we provide is what is right for you and your health and we use

Why Understanding TRT is Essential to Your Health Journey

is a game changing option for men experiencing the of low (Low T), those aged 40 upwards. With from energy to improved muscle tone and mood, TRT can make a big difference to the quality of your life. However, as with any medical treatment, understanding both it’s benefits and risks is essential for decision-making.


At Omniya Clinic London, we’re committed to you through this journey with clear, research-based . Let’s break down the potential risks, safety considerations, and side effects of TRT, so you can feel confident in your decision-making process.

What Are the Risks of Testosterone Replacement Therapy?

Although is generally considered safe when administered and monitored by qualified professionals, risks are associated with the treatment. These risks are often tied to individual health factors and careful and . These risks can include cardiovascular concerns, with health, of pre-existing sleep apnoea and .


One of the most discussed concerns with TRT is it’s impact on heart health. presented mixed findings in this area until early 2024 when the large double blinded study known as provided compelling evidence to say that on TRT are not at an increased risk of cardiovascular events to the public(1). There is an excellent review subsequently by Hackett titled "Long Term Cardiovascular Safety of Testosterone Therapy: A Review of the TRAVERSE Study", which summarises the of what is one of the largest and most robust studies on the risks and benefits of TRT(2).


At Omniya Clinic, we pre-treatment to determine each patient’s cardiovascular health, TRT is safe for those with or pre-existing heart conditions.


The therapy and prostate health has been a subject of for . Historically, some avoided TRT due to concerns that it could cancer growth. However, according to the Endocrine Society’s clinical guidelines(3), recent data does not support a direct link and an increased risk of prostate cancer in healthy men. Nonetheless, the guidelines recommend regular monitoring for those undergoing TRT. In line with this recommendation, our team at Omniya follows a careful monitoring protocol to safeguard prostate health.


TRT can potentially worsen sleep apnea, a condition that during sleep, particularly in men who are overweight. Longterm risks of sleep apnoea include heart attacks and strokes. Research published in the of highlights that Testosterone Replacement Therapy (TRT) may play a role in airway resistance, which can sleep apnoea symptoms(4). Importantly, one of the common presenting symptoms of a patient with low is difficulty losing weight and weight gain; this is also one of the commonest causes of sleep apnoea. TRT weight loss and muscle gain and therefore can be in the reversal of sleep apnoea. At Omniya, our initial a of any sleep disorders, us individuals at risk and adjust as needed. It is important if we feel someone may have sleep apnoea that this is and (and if required) first, before starting TRT.


For more information, please see our page on .


By supplementing testosterone, the body may reduce its own production of the hormone, which can lead to lower sperm production. This is an for men planning to start or expand their . To this risk, adjunctive treatments like human chorionic (HCG) can sometimes be used alongside TRT. have found that HCG therapy could help sperm production in men testosterone therapy, more research is needed in this area, particularly around the longterm use of HCG to fertility(5).

Safety Measures at Omniya Clinic

safety is at the heart of our at Omniya Clinic. Here’s how we ensure that every treatment is safe, effective, and personalised:




What are the Side Effects of Testosterone Replacement Therapy (TRT)?

Just as with any treatment, can have side effects. However, most side effects are mild and manageable. Here are some that you may encounter:


The good news is that many of these side effects are manageable with or changes to your treatment plan. At Omniya Clinic, our team is on hand to guidance and support every step of the way.

Long-Term Considerations: What Does the Research Say?

The long-term impact of is a area of research. While early studies raised questions, more recent findings are the potential for benefits, particularly in areas like bone health, cognitive function, and health.




Making an Informed Decision

Choosing is a highly personal decision that the and risks. At Omniya, we encourage all to have open with our specialists, their symptoms, goals, and any questions they may have. Here are some steps to consider when thinking about TRT:


We believe that knowledge is power. Our mission at Omniya Clinic is to every patient with the they need to make informed decisions about their health and .


to TRT options.

The Path to Renewed Vitality Starts Here

can be a treatment for men with low testosterone. By understanding its risks, safety considerations, and side effects, you can make an empowered that aligns with your health goals. At Omniya Clinic London, our team is to safe, effective, and care, you optimal health and .


If you’re of low and are considering TRT, take the first step towards renewed energy, confidence, and vitality with Omniya Clinic. Our team of experts is ready to guide you on your to better health.


to start your with TRT


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Acne or Oily Skin: Testosterone can increase oil production in the skin, leading to mild acne in some men. Optimisation of your hormone levels, appropriate skincare and sometimes medication to treat acne are some of the ways that our specialists will manage this problem.
Fluid Retention: Some men experience mild fluid retention, especially in the early stages of treatment where it will often resolve after the first few weeks.
Increased Red Blood Cell Count: Testosterone can elevate red blood cell levels, which may lead to a risk of blood clots. Regular blood tests can help monitor and manage this.
Breast Tenderness or Enlargement: Known as gynaecomastia, this side effect is relatively rare and often resolves with dose adjustments. Your doctor will advise you on what to look out for so as to prevent this.
Changes in Cholesterol Levels: TRT can affect cholesterol, requiring periodic blood tests to monitor cholesterol levels. A healthy diet and lifestyle can help mitigate this effect." } ]








Dr Aman Chungh is a highly regarded men’s health physician and medical author whose work the gap between and health education. With over a decade of in general practice, he has an approach that insights from medicine, and holistic health. His clinical journey has deepened his of the complex interplay between hormones, mental well‐being and physical - a perspective that enriches his written to the field.


A proud of the University of Southampton, Dr Chungh obtained his Bachelor of and Bachelor of Surgery degree in 2014, following his in both a Bachelor of Science and a Bachelor of Medical Sciences. This robust foundation, with years of hands‐on care, fuels his commitment to remaining at the forefront of . As an author, he skilfully translates principles into engaging, reader�[https://Labellemedicalclinic.com/ �friendly] content, enabling both and the general public to appreciate the nuances of modern men’s health.


Dr Chungh is by a compassionate, patient� . He the of barriers to care, believing that an informed is an empowered one. His work not only his diagnostic and therapeutic prowess but also his dedication to collaborative care, treating every with the same empathy and respect he would offer his own family.


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 | 28 November 2024


 | 28 November 2024


 | 28 November 2024


/ / Safety Profile of TRT